The structure within a eukaryotic cell that contains the vast majority of its genetic information.
Human eggs appear to be protected from the age-related accumulation of genetic mutations in mitochondrial DNA (mtDNA)...
Dr Andy Greenfield explores what it took to achieve the birth of eight healthy babies with donated mitochondria – not just scientific and technical advances but also ethical inquiry, public and patient engagement, the introduction of new laws and regulations, and the careful establishment of a new clinical pathway...
Eight children have been born in the UK following mitochondrial donation IVF. All eight children have made normal developmental progress, and none of them show any sign of mitochondrial disease...
Exercise can induce protective gene activity in the brain cells of Alzheimer's model mice, uncovering new understanding of disease mechanisms...
Several epigenetic pathways have been found to play a role in the spatial organisation of DNA during early embryonic development in mice...
A novel way to control CRISPR genome editing using focused ultrasound has been discovered...
Circular DNA existing outside chromosomes can drive cancer growth and is a potential drug target, according to three papers published this week in Nature...
The transposon LINE1 is an essential regulator in early human development, researchers found...
A map of DNA alterations in two regions of the developing human brain has been created...
Genome editing using small protein structures has the potential to be more efficient, with increased specificity, than current methods – such as CRISPR/Cas genome editing...
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