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PETBioNewsGlossaryOrganoid

BioNews

Organoid

An artificially grown mass of cells or tissue that resembles an organ.

54 articles
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
20 June 2022 • 3 minutes read

Brain organoids reveal effect of sodium valproate on prenatal brain

by Dr Emma Green

New research using brain organoids suggests that stem cell senescence, where cells are halted in a suspended state, is responsible for the fetal brain changes caused by sodium valproate...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
23 May 2022 • 2 minutes read

Process for developing organoid models of the cervix published

by Ochuko Oyeye

Details of how to develop three-dimensional organoid models of the cervix have been published...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
4 February 2022 • 2 minutes read

Brain organoids reveal genetic mutations affect emergence of neurons in people with autism

by Tom Turner

Mutations in three autism-associated genes have been shown to affect the pace that certain types of neurons emerge in the developing brain...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
3 December 2021 • 2 minutes read

Multi-layered stomach organoids created from human stem cells

by Dr Ara Schorscher-Petcu

For the first time, scientists have engineered a miniature stomach, which displays cellular and functional complexity similar to its human counterpart...

PET BioNews
News
17 September 2021 • 2 minutes read

Pancreatic organoids grown on synthetic structure give insight into cancer

by Semyon Bodian

Pancreatic organoids, grown using a newly developed gel, have enabled scientists to better understand pancreatic cancer...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
3 September 2021 • 2 minutes read

Researchers grow mini human lungs to imitate COVID-19 infection

by Abbie Harper

The first human 'lung-in-a-dish' model, known as a lung organoid, representing all lung cell types and allowing replication of SARS-CoV-2 infection has been produced...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
20 August 2021 • 2 minutes read

Lab-grown brain organoids develop primitive eyes

by Dr Emma Green

Brain organoids grown in the lab can develop primitive eyes called optic cups, containing key cell types that are able to respond to light...

PET BioNews
News
30 July 2021 • 2 minutes read

Cerebral organoids show early signs of dementia

by Beatrice Costa

A mutated protein associated with Alzheimer's disease may trigger the death of brain cells known to be vulnerable in frontotemporal dementia...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
23 July 2021 • 2 minutes read

Stem cell model reveals how SARS-CoV-2 infects the brain

by Jessica Peixinho

A stem cell model has been developed to highlight the route of infection of the brain by SARS-CoV-2, the virus that causes COVID-19...

Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
CC BY 4.0
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
2 July 2021 • 2 minutes read

Most sophisticated in vitro mouse embryo created from stem cells

by Stella Hume

A mouse embryo has been developed artificially in a lab from embryonic stem cells that represents the most sophisticated in vitro mammalian model ever created...

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