An artificially grown mass of cells or tissue that resembles an organ.
Human salivary gland organoids derived from pluripotent stem cells have been transplanted into mice....
Human organoids transplanted into mouse brains can grow and form connections with the surrounding nervous system...
Dr Naomi Moris and an international group of colleagues propose three broad categories of ethical value and five categories of morally relevant biological features that can inform oversight of research involving human stem-cell-based embryo models...
Human brain organoids have been kept in culture for more than five years, extending the period over which these models of human brain development have previously been maintained...
Gene therapy designed to deliver a healthy copy of the ALPK3 gene can restore heart function, raising the possibility of a future treatment for some forms of inherited cardiomyopathy...
A comprehensive biobank of patient-derived tumour organoids has been developed to map genes that cancer cells depend on for growth and survival...
A developmental mechanism that restricts nerve regeneration has been identified using neural organoids...
Professor Lorenz Studer and Tyler Lamb argue that existing ethical oversight enables responsible human embryonic stem cell research, and that continued NIH support is vital for regenerative medicine, disease modelling and new therapies...
Three-dimensional cerebral organoids suggest that Ebola virus can establish long-term infection in the human brain...
Coordinated best practice guidance and a pivot to a forward-looking regulatory approach to emerging biotechnologies can enable neural organoid research to flourish responsibly, protecting ethical standards and public confidence...
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