Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
BioNews
SCBEM (stem-cell-based embryo model)
A stem-cell-based embryo models (SCBEM) is a coherent multicellular structure that – in some respects – resembles an embryo in the earliest stages of development.
SCBEMs are created in the laboratory from stem cells, rather than from eggs and sperm.
59 articles
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
Embryos implant in 3D womb lining models
Both natural human embryos and stem cell-based embryo models have been observed implanting in cultured models of the human endometrial lining...
Understanding human embryo implantation: A research breakthrough
Professor Robin Lovell-Badge – chair of trustees at PET – discusses three new studies exploring human embryo implantation, and argues that while the research represents an important breakthrough, it should not be misconstrued as a step toward ectogenesis...
Event Review: HDBI Ethics Seminar – Ethics oversight in developmental biology research
Speakers highlighted the need for interdisciplinary dialogue between ethicists and researchers when considering ethical research involving stem cell-based-embryo models...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Stem-cell-based embryo model mimics human blood development
A stem-cell-based embryo model capable of producing human blood cells has been created in the lab, mimicking early embryonic development...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Complexity without ethics: Why integration matters for embryo models
Dr Hafez Ismaïli M'hamdi – from the department of health, ethics and society at Maastricht University, the Netherlands – argues that distinction between integrated and non-integrated embryo models still matters…
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Robert Edwards at 100: Remembering an IVF Visionary
The enduring legacy of Professor Sir Robert Edwards' life and work was explored in an online event produced by PET, in partnership with the Association of Reproductive and Clinical Scientists...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
From nuclear bombs to nuclear genomes
Professor of stem cell science, Dusko Ilic, discusses concerns raised by the plans of a US-based startup – the (new) Manhattan Project – to create genome-edited babies…
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Event Review: A Question of Science – What's the future of fertility?
Dr Tatiana Giovannucci attended the live recording of 'What's the Future of Fertility?', part of the podcast series A Question of Science, and Professor Brian Cox's first project as Crick scholar...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Mouse stem-cell-based embryo models mimic natural blastocysts
Mouse stem cells have been used to create an embryo model that mimics the stage where an embryo implants into the uterus...