Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
Vector
A delivery system used in the laboratory to carry foreign DNA into a cell. Modified viruses are commonly used as vectors in gene therapy.
88 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Spotting the zebras among the horses: Understanding metabolic disorders
Metabolic disorders can seem forbiddingly complex, but a simplified approach to explaining their biological basis can lead to improved understanding, earlier diagnosis and better management, argues Dr Srividya Sreekantam...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
New approach to delivering gene therapy for cystic fibrosis
A lipid nanoparticle-based gene therapy for cystic fibrosis restores biological function in a preclinical model...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
First patient treated with gene therapy to improve heart bypasses
A heart attack patient has become the first person to be treated in a clinical trial of an experimental gene therapy, which aims to strengthen blood vessels after coronary bypass surgery...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Pioneering gene therapy for Hunter syndrome shows clinical success
A UK toddler with a rare genetic condition was the first person to receive a new gene therapy that appears to halt disease progression...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
First evidence that gene therapy can slow Huntington's disease
A microRNA treatment is the first therapy to show evidence of slowing Huntington's disease progression....
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
DNA-coated nanostructures enhance CRISPR delivery and precision
A new nanostructure has been developed that could enable CRISPR genome-editing components to enter human cells more efficiently and safely...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Genome editing research targets late-onset Tay Sachs
Base editing has been used to correct the mutation causing late-onset Tay-Sachs disease in mice and human cells...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Rare immune disease treated successfully with personalised gene therapy
A world-first gene therapy has successfully been used to restore the immune system of a teenager with a rare genetic condition...