Genetic variants discovered that increase risk of PCOS
A genome-wide association study has identified three genetic variants associated with increased risk of polycystic ovary syndrome in Finnish and Estonian women...
News
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Women sue over lack of pain relief during egg retrieval
Seven women have accused a US fertility clinic of failing to safeguard its supply of opioid painkillers after a nurse replaced fentanyl with saline...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CRISPR genome editing may select for cells with cancer-associated mutations
Cells with mutations linked to cancer can outcompete normal cells after CRISPR/Cas9 genome editing...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
200,000 whole genomes sequenced by UK Biobank available to researchers
The first 200,000 whole genomes to be sequenced as part of the UK Biobank project have been made widely available to researchers...
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
No difference in viability found between mosaic and non-mosaic embryos
Many IVF embryos discarded due to chromosomal abnormalities could lead to viable pregnancies and healthy babies, a new non-selection clinical trial has suggested...
Switzerland's marriage equality law widens access to IVF
Same-sex couples in Switzerland will be able to marry from July 2022 and will have the same access to assisted reproduction as heterosexual couples...
Researchers shed light on genetics of endometrial cancer risk
Using a tissue-specific genetic association study, researchers have identified eight genes associated with an increased risk of endometrial cancer...
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
Early stage of human embryo development seen for the first time
High-resolution single-cell gene expression analysis has been performed on a gastrulating human embryo, providing landmark insights...
Reviews
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Podcast Review: DNA Today – dementia
DNA Today is a weekly podcast which aims to 'educate the public on genetic and public health topics.' In this episode on dementia, host Kira Dineen spoke with biochemist Dr Dayan Goodenowe...
Podcast Review: Surrogacy Abroad and in the UK
Hearing successes is, I think, just so powerful'. These are the words of Anna Buxton, a mother through surrogacy and interviewee on a Fertility Podcast episode...
Comment
FILM: Sarah Norcross and Dr Charles Steward discuss whole genome sequencing and newborn screening
by BioNews
A conversation between Sarah Norcross (director of the Progress Educational Trust) and Dr Charles Steward (lead for patient advocacy and engagement at Congenica, and parent of two children with severe neurological disorders)...
Unproven stem cell treatment industry in the USA: a concerning boom
by Dr Patrick Foong
In the USA, clinics offering stem cell therapies not approved by the US Food and Drug Administration expanded four-fold in just five years...
Whole Genome Sequencing at Birth: What Should Be Looked For? What Should Be Fed Back?
by Dr Jess Buxton
A new pilot study embedded in the NHS will explore whether and how to offer whole genome sequencing to newborn babies...