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Allogeneic

Refers to cells or tissues from different individuals.

In an allogeneic stem cell transplant, a patient is treated with donor stem cells from a healthy individual.

3 articles
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false-coloured cryogenic scanning electron micrograph).
News
15 May 2020 • 1 minute read

Critical window for re-infection with HIV after stem cell transplantation

by Dr Molly Godfrey

New research, in HIV positive patients being treated for blood cancer, has identified a critical time window after donor transplantation, during which the expanding donor cells are particularly vulnerable to being infected with HIV.

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
20 September 2017 • 2 minutes read

Gene therapy for cancer halted after patient death

by Ebtehal Moussa

Two trials assessing gene therapy for blood cancer have been put on hold by the US Food and Drug Administration, following a patient fatality...

Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Comment
7 March 2016 • 4 minutes read

Growing sperm in the lab: an embryonic science

by Dr Dusko Ilic

A recent announcement that scientists had created functioning spermatozoids from mouse embryonic stem cells in the lab made quite a splash in the media. However, one key point seemed to be overlooked...

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BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.

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