PGT-A may overestimate impact of embryo abnormalities
A common IVF 'add-on' – preimplantation genetic testing for aneuploidy (PGT-A) – may overestimate the impact of embryo abnormalities, new research suggests...
BioNews
Aneuploidy
An abnormal number of chromosomes, either too few or too many. Nearly all human body cells usually have a set of 46 chromosomes, while egg and sperm cells have 23.
124 articles
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Cannabis use may affect women's eggs
Cannabis may directly interfere with women's ability to conceive by affecting the health of their eggs...
PGT-A might reduce unsuccessful embryo transfers in over 35s
Genetic testing of IVF embryos could help more women over 35 have a baby in less time, according to a small study focused exclusively on women aged 35-42...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Fertility regulator survey reveals widespread use of IVF add-ons
Almost three-quarters of UK fertility patients used a treatment 'add-on', according to the Human Fertilisation and Embryology Authority's National Patient Survey 2024...
Fresh embryos may increase chance of IVF success for some women
Fresh embryo transfer could be the most effective option for women with a low likelihood of achieving a live birth through IVF...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Non-judicious uptake of PGT-A in Malaysia is driven by sociocultural factors
Associate professor of biomedical science at Peking University, China, Dr Alexis Heng Boon Chin, discusses the rise in preimplantation genetic testing for aneuploidy in Malaysia...
Image by K Hardy via the Wellcome Collection. Depicts a human embryo at the blastocyst stage (about six days after fertilisation) 'hatching' out of the zona pellucida.
Early mouse embryos are prone to DNA replication errors
During the first cell divisions of mouse embryos a period of instability has been uncovered, which translates into chromosomal errors...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Event Review: Polygenic Embryo Screening – The promise and perils of selecting our children's traits
A timely conversation focused on the bioethical concerns wrapped up in the clinical use of polygenic embryo screening...
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
Event Review: The Impact of Dobbs on Emerging Reproductive Technologies
Doctors and lawyers got together to discuss the intricacies of the impact of the overturning of Roe v Wade on reproductive healthcare in the USA…