BioNews
iPS (induced pluripotent stem) cell
A cell with similar properties to an embryonic stem cell, but created in the laboratory by 'reprogramming' cells from adult tissues, such as skin cells.
272 articles
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
Embryo research and stem cells in France: What might change?
France will need to update its bioethics law by 2028. Adrien Bottacci explains what recent recommendations could mean for the 14-day limit on human embryo research, and for research involving stem-cell-based embryo models...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Alzheimer's risk gene may change fat processing in brain cells
A genetic variant linked to Alzheimer's disease impairs the production of the fatty layer that insulates neurons by disrupting an important signalling pathway...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
'Old' human blood cells transformed into 'young' brain cells
Researchers have turned an 80-year-old's blood precursor cells into neural stem cells, resetting the cells' 'biological age' in the process...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Salivary gland organoids developed from human pluripotent stem cells
Human salivary gland organoids derived from pluripotent stem cells have been transplanted into mice....
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Giving more choices to survivors of childhood cancer
Researchers working in childhood cancer survivorship explain how patient-derived stem cells could one day expand fertility restoration options, for boys whose cancer treatment has damaged their developing testes…
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Human brain develops from two distinct groups of cells
The origins of the human brain can be traced back to two distinct groups of cells in the developing embryo...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
TV Review: Dolly – The world's most famous sheep
Dolly the sheep became a global scientific celebrity when she was revealed in 1997. This documentary revisits her cloning, exploring both the science behind her creation and the ethical questions that captured the public imagination…
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene therapy restores heart function in mice and human heart organoids
Gene therapy designed to deliver a healthy copy of the ALPK3 gene can restore heart function, raising the possibility of a future treatment for some forms of inherited cardiomyopathy...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Stem cell transplantation shows safety in first-in-human spinal cord injury trial
Transplanting neural stem/progenitor cells into people with recent spinal cord injuries has provided early evidence that the approach can be delivered safely, according to a first-in-human study published in Nature Medicine...