New FDA guidance may speed up gene therapy development
The US Food and Drug Administration has proposed allowing manufacturers of cell and gene therapies to make use of existing scientific and platform knowledge during product development...
Relating to genetic information that cannot be inherited by the next generation (all body cells apart from egg and sperm cells, and their precursors).
by Evie Ribeiro
The US Food and Drug Administration has proposed allowing manufacturers of cell and gene therapies to make use of existing scientific and platform knowledge during product development...
Delivery of messenger RNA into the testes of infertile mice can reactivate spermatogenesis...
The children of men exposed to radiation following the Chernobyl nuclear reactor incident in 1986 show specific patterns of DNA mutations, providing evidence that radiation-induced changes in sperm can affect offspring...
Disruption to a gene causes malformations to the development of sperm tails, resulting in mice producing no functional sperm...
An advanced DNA sequencing tool can identify previously undetectable genetic mutations in human tissue with high accuracy...
Professor Sir John Gurdon, pioneer of developmental biology and Nobel Prize winner, has died aged 92...
Egg cells have been created from human skin cell DNA, which have then been fertilised with sperm to create embryos...
Single-nucleotide differences in a DNA sequence that are associated with an inherited cancer risk have been identified through a large-scale screening study...
Subtle changes in the brain can be identified decades before a diagnosis of Huntington's disease, two major new studies that shed light on what drives the disease have shown...
Unrepaired DNA damage lingers longer within cells than previously thought, potentially increasing cancer risk...
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