ICSI and ovarian stimulation linked to different patterns in children's DNA
Parental age and various procedures used during assisted reproductive technology have been linked to different patterns of mutational changes in the DNA of offspring...
BioNews
Whole Genome Sequencing (WGS)
Determining the order of every base in an organism's genome. Differs from genotyping, which only looks at a specific subset of genetic variants.
109 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
The Genetics of Infertility: Causes, Choices and Treatments
Genetic testing is beginning to identify causes of infertility that were previously unexplained. PET's latest event brought together clinicians and researchers to discuss the opportunities and limitations of reproductive genetics...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Newborn genomic screening identifies ALD risk in two brothers
A baby taking part in the Generation Study has been identified as carrying a mutation linked to the rare condition adrenoleukodystrophy, prompting his older sibling to also be tested...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Can PGT-A give us an accurate picture of the genetic content of embryos?
PGT-A is widely used to assess the chromosome status of IVF embryos, but how accurately can a biopsy of just a handful of cells predict an embryo's genetic makeup? Dr Desislava Staneva explains why interpreting PGT-A results is more complex than it may first appear...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Recessive gene variant causes neurodevelopmental disorder
A newly described neurodevelopmental disorder has been linked to changes in a small noncoding gene...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Scotland introduces newborn screening for spinal muscular atrophy
The Scottish Government has launched newborn screening for spinal muscular atrophy, allowing earlier diagnosis and access to potentially life-changing treatment...
Event Review: Testing Embryos – How far should we go?
The first in a series of discussions on human reproduction from the Hastings Centre for Bioethics asks today's most pressing questions about embryo selection…
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Non-coding gene discovered to be a cause of blindness
New genetic causes of inherited blindness have been discovered that may offer answers to families with unexplained vision loss...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.