Clustered regularly-interspaced short palindromic repeats.
Naturally occurring in bacteria, segments of DNA used for defence against pathogens.
Used by humans in genome editing: the CRISPR/Cas system used to edit DNA at specific locations in the genome.
A single-dose CRISPR-based genome-editing therapy for hereditary angioedema has shown positive Phase 3 clinical trial results and entered a step-by-step approval process with US regulators...
A new CRISPR-based approach has been designed to selectively eliminate human cells with disease-causing genes in vitro...
Breakthrough Prizes in Life Sciences have been awarded to two teams of scientists for their work on gene therapies for inherited blood and blindness conditions...
An artificial intelligence model trained on genomic data can predict disease-causing mutations and design synthetic viruses...
A topical CRISPR-based genome-editing therapy has been developed to address disease-causing mutations responsible for inherited human skin disorders...
CRISPR/Cas9 genome editing has been used in mice to investigate two key genes' roles in male fertility and sperm production...
A new genome editing approach has been shown to safely and efficiently remove the source of transthyretin amyloidosis in mice, demonstrating greater therapeutic opportunities for genome editing...
A large-scale study has unveiled genes essential for early brain development and uncovered the cause of a previously unrecognised neurodevelopmental disorder...
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