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PETBioNewsGlossaryCRISPR

BioNews

CRISPR

Clustered regularly-interspaced short palindromic repeats.

Naturally occurring in bacteria, segments of DNA used for defence against pathogens.

Used by humans in genome editing: the CRISPR/Cas system used to edit DNA at specific locations in the genome.

175 articles
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
CC BY 4.0
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells showing the stages of cell division (starting with interphase at the top and progressing anticlockwise, the stages shown are prophase, prometaphase, metaphase, early anaphase, anaphase and telophase).
Reviews
20 June 2022 • 4 minutes read

Podcast Review: How Far Could Genome Editing Go?

by Clíona Farrell

The BBC's CrowdScience podcast calls on listeners to ask the scientific questions they've always wanted answered, from medicine, to the Earth and beyond. In the latest episode of the series, host Caroline Steel delves into the world of genome editing, from success stories in the clinic, to the pragmatic ethical concerns...

Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family entwined in coils of DNA (based on the figure of Laocoön from Greek and Roman mythology).
Comment
20 June 2022 • 6 minutes read

An adaptive act: How should human fertilisation and embryology legislation respond to scientific and technological change?

by Julian Hitchcock

How responsive is the Human Fertilisation and Embryology Act to the pace of social and technological change? In this comment, Julian Hitchcock contemplates revision of the Act, and how might we optimise its responsiveness to clinical need while upholding standards...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
6 May 2022 • 2 minutes read

Single mutation discovered may be genetic cause of lupus

by Sneha Krishnamurthy

A novel mutation in a gene called TLR7 has been identified as directly linked to the development of lupus...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
8 April 2022 • 2 minutes read

Genes affecting HIV infection identified using CRISPR genome editing

by Devika Sooklall

Genome editing of blood could provide new treatments for HIV according to a new study...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
1 April 2022 • 2 minutes read

Research into creating cats that do not cause people allergies

by Tom Turner

CRISPR genome editing has been tested in feline cells on the genes that cause allergic reactions in humans, potentially paving the way to hypoallergenic cats...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Comment
7 March 2022 • 6 minutes read

Editing the Human Genome: Where Are We Now? What Happens Next?

by Dr Alexander Ware

The Progress Educational Trust recently arranged a lineup of key figures at the vanguard of different aspects of genome editing, who, during the event, canvassed their opinions and current research...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
4 March 2022 • 2 minutes read

Jailed scientist Dr He Jiankui should be made 'responsible' for children whose genomes he edited

by Jakki Magowan

Two prominent Chinese bioethicists have recommend the jailed scientist, Dr He Jiankui, be made financially, morally and legally responsible for the health and wellbeing of the children he genome-edited...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
4 March 2022 • 3 minutes read

Broad Institute wins CRISPR genome editing patent case

by Tom Turner

The Broad Institute, Cambridge, Massachusetts, has been awarded the US intellectual property rights for the use of CRISPR/Cas9 by a Patent and Trial Appeal Board...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
News
4 March 2022 • 2 minutes read

CRISPR genome editing treatment still effective after one year

by James Moore

The first team to use CRISPR to edit a disease-causing gene in humans has found the effects are persistent up to a year later...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
CC BY 4.0
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Reviews
4 February 2022 • 5 minutes read

Event Review: Dreams and Nightmares of the Genetic Age

by Anna Wernick

In his loud shirt, covered in green leaves and plants, the University of Manchester's professor of Zoology, Matthew Cobb, was dressed appropriately for this evening's talk...

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