Clustered regularly-interspaced short palindromic repeats.
Naturally occurring in bacteria, segments of DNA used for defence against pathogens.
Used by humans in genome editing: the CRISPR/Cas system used to edit DNA at specific locations in the genome.
Data on the effectiveness and safety of Casgevy gene therapy in children aged five to 11 years has been reported...
A new method for identifying small amounts of DNA from cancer cells in the blood may offer further opportunities for early cancer detection...
Disruption to a gene causes malformations to the development of sperm tails, resulting in mice producing no functional sperm...
A UK toddler with a rare genetic condition was the first person to receive a new gene therapy that appears to halt disease progression...
CRISPR-based genome editing has been used to overcome chemotherapy resistance in lung tumours by disabling a tumour-specific mutation...
The UK government has committed to accelerating the development and approval of treatments for rare diseases, through major reforms to current regulation...
CAR-T cell cancer treatments could be made safer and more durable by reprogramming T cells without altering their DNA, according to new research...
Professor of stem cell science, Dusko Ilic, discusses concerns raised by the plans of a US-based startup – the (new) Manhattan Project – to create genome-edited babies…
CRISPR/Cas9 has been used to identify genome editing targets that significantly enhance the efficiency of a targeted therapy for myeloma, a type of cancer...
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