BioNews
CRISPR
Clustered regularly-interspaced short palindromic repeats.
Naturally occurring in bacteria, segments of DNA used for defence against pathogens.
Used by humans in genome editing: the CRISPR/Cas system used to edit DNA at specific locations in the genome.
Two gene therapies for sickle cell disease approved by FDA
Two gene therapies for the treatment of sickle cell disease have been approved by the US Food and Drug Administration...
Thalassaemia patients to qualify for NHS stem cell transplants
Adults with thalassemia, a severe genetic blood disorder, will be offered potentially curative stem cell transplants on the NHS for the first time...
Research into gene therapy reveals blood cancer risk
A gene therapy treatment for sickle cell disease has led to a build-up of cells with genetic mutations that make them grow faster, increasing blood-cancer risk, researchers revealed...
Unintended consequence of CRISPR/Cas9 genome editing discovered
CRISPR/Cas9 genome editing can result in the unintended deletion of a region associated with cancer...
CRISPR base editing therapy cuts high cholesterol in early trial
CRISPR base editing therapy reduced cholesterol levels in the blood of a small cohort of patients, clinical trial interim data has shown...
First CRISPR therapy evaluated by FDA advisers
A CRISPR-based treatment for sickle cell disease is one step closer to approval after an advisory committee for the US Food and Drug Administration met to review its safety...
Clinical data presented on first genome editing treatment for HIV
Early safety data of a potential CRISPR-based genome editing therapy for HIV have been reported...