CRISPR therapy treats rare genetic inflammatory disorder
A single dose of a CRISPR-based gene therapy could cure inflammation in people affected by a rare condition that causes life-threatening swelling attacks, according to a new clinical trial...
Making deliberate alterations to the DNA sequence at targeted locations in the genome. This can include deleting, inserting or replacing sections of DNA. Several approaches are used to achieve these changes, include zinc finger nucleases (ZFNs), TALENs, CRISPR/Cas and base editing.
A single dose of a CRISPR-based gene therapy could cure inflammation in people affected by a rare condition that causes life-threatening swelling attacks, according to a new clinical trial...
by Yan Lau
A genome-edited pig liver effectively filtered blood in a brain-dead man for three days, showcasing a potential temporary solution for acute liver failure...
Brain organoids developed from fetal tissue offer a new way to model brain diseases and aid in drug testing....
by BioNews
Two gene therapies for the treatment of sickle cell disease have been approved by the US Food and Drug Administration...
by BioNews
Adults with thalassemia, a severe genetic blood disorder, will be offered potentially curative stem cell transplants on the NHS for the first time...
by Yan Lau
A gene therapy treatment for sickle cell disease has led to a build-up of cells with genetic mutations that make them grow faster, increasing blood-cancer risk, researchers revealed...
CRISPR/Cas9 genome editing can result in the unintended deletion of a region associated with cancer...
by Olivia Goff
CRISPR base editing therapy reduced cholesterol levels in the blood of a small cohort of patients, clinical trial interim data has shown...
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.