MRI used to show brain methylation
A new magnetic resonance imaging technique has allowed scientists to observe epigenetic changes in the brain.
BioNews
Methylation
The biochemical process by which methyl groups are added to another chemical group or molecule. Methylation of DNA at specific locations in the sequence is a form of epigenetic regulation.
35 articles
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
Epigenetic information from cervical smear samples could help detect ovarian and breast cancer
Cells in cervical smear test samples could be used as an indicator for breast and ovarian cancer, and show promise as tools for monitoring cancer risk...
Unique epigenetic profile found in identical twins
Identical twins carry a unique epigenetic signature on their DNA, providing potential clues as to how and why identical twinning occurs...
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Functional sperm developed from mouse pluripotent stem cells
Researchers in Japan have successfully demonstrated the development of functional sperm cells that developed into fertile offspring from pluripotent embryonic stem cells, in mice...
Reversal of biological age detected in mouse and human embryos
Germline cells seem to reset their biological clocks around the time of embryo implantation, not when generating gametes, as previously thought...
Machine learning technique detects epigenetic drivers of cancers
Machine learning has been used to predict whether certain epigenetic changes are likely to lead to cancer...
PARP inhibitor is most effective in ovarian cancer patients with DNA repair mutations
New research suggests mutations in multiple DNA repair genes can determine how well ovarian cancer patients will respond to the PARP inhibitor, rucaparib...
No growth or development differences for children conceived via IVF
Newborns conceived via IVF appear to have lower levels of DNA methylation at certain regions of DNA, when compared to newborns conceived without IVF...
Novel CRISPR approach uses an on-off switch for epigenome editing
Reversible genome-wide epigenetic editing may be possible with a new approach using cellular memory to silence gene expression...
Epigenetic clock gives insight into brain ageing and dementia
A novel body clock has been developed which can predict our brain's age and how prone we are to dementia...