Genetic information located within mitochondria, the cell's energy generators, rather than in the nucleus. Mitochondrial DNA is inherited solely through the maternal line, as sperm contribute no mitochondria to the fertilised egg.
Although sperm cells do contain some mitochondria, scientists have found that these mitochondria do not contain intact mitochondrial DNA...
A new test detects mitochondrial DNA damage in blood cells collected from patients with Parkinson's disease...
Mitochondrial genes in the heart, kidney, liver and lymph nodes are downregulated following COVID-19, findings in humans and mice have shown...
Luke Steventon reviews a radio programme about mitochondria, which are described as producing energy production levels of '30 million volts per metre – like a bolt of lightning'...
The birth of the first UK child(ren) with donated mitochondria has been confirmed by the Human Fertilisation and Embryology Authority...
An innovative therapy aiming to treat mitochondrial disease has shown encouraging results in six children...
Transfer of mitochondrial DNA into the nuclear genome occurs in one in every 4000 births...
Mechanisms directly linking mitochondrial dysfunction to the shortening of telomeres have been discovered, alongside a novel optogenetic technique, which uses light to restore normal function to the mitochondria...
A newly discovered link between mitochondria, inflammation and two genes required for blood cell growth could provide new therapeutic options to treat atherosclerosis and other inflammation-associated diseases...
How responsive is the Human Fertilisation and Embryology Act to the pace of social and technological change? In this comment, Julian Hitchcock contemplates revision of the Act, and how might we optimise its responsiveness to clinical need while upholding standards...
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