TALED genome editing approach targets mitochondrial DNA
An approach which significantly improves the ability to modify mitochondrial DNA in living cells has been developed by scientists in South Korea...
BioNews
mtDNA (mitochondrial DNA)
Genetic information located within mitochondria, the cell's energy generators, rather than in the nucleus. Mitochondrial DNA is inherited solely through the maternal line, as sperm contribute no mitochondria to the fertilised egg.
127 articles
Mitochondrial donation becomes legal in Australia
The Australian Senate has passed a bill which will legalise the clinical use of mitochondrial donation by a vote of 37 votes for to 17 against...
Mitochondrial donation bill passed in Australia
A bill permitting mitochondrial donation has been passed by the Australian House of Representatives...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Advances in Assisted Reproduction: What Can We Expect?
Sarah Norcross, director of the Progress Educational Trust, invited the audience of the event to consider where assisted reproductive technologies stood 55 years ago...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
TV Review: DNA Family Secrets
As a human geneticist I've always been interested in anything DNA-related, whether this is a book, research paper, film, or documentary. I never expected, however, that DNA would be the focus of a semi-documentary/semi-intellectual reality TV show, hosted by Stacey Dooley...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Mitochondria linked to stem cell transplant rejection
A new study has shown why stem cell transplants, even derived from the patient's own cells can be rejected...
DNA study may have implications for mitochondrial donation
Mitochondria are not as interchangeable as originally thought, with implications for the selection of donors for mitochondrial donation...
Native American man's DNA traced back 17,000 years
A Native American man in Montana has the 'oldest' human DNA in the United States, according to news reports...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
First baby born in mitochondrial donation for infertility trial
A baby conceived via IVF using genetic information from three people has been born to a mother not affected by mitochondrial disease...
Mitochondrial DNA can be inherited from fathers
A new paper documents three unrelated families where paternal mitochondrial DNA is present in offspring...