Mitochondrial donation case study finally published after 13 years
Chinese researchers say an IVF technique called pronuclear transfer can safely produce a viable pregnancy...
Genetic information located within mitochondria, the cell's energy generators, rather than in the nucleus. Mitochondrial DNA is inherited solely through the maternal line, as sperm contribute no mitochondria to the fertilised egg.
Chinese researchers say an IVF technique called pronuclear transfer can safely produce a viable pregnancy...
A match of mitochondrial and nuclear genomes apparently affects healthy ageing in mice. But key questions need to be answered before stirring up implications for human mitochondrial replacement therapies...
The interaction between mitochondrial and nuclear DNA may have implications for health, metabolism and ageing, according to a new study...
by Ayala Ochert
A roundup of research stories from the annual meeting European Society of Human Reproduction and Embryology that hit the headlines this week...
Researchers have identified a gene that, when activated, causes mitochondria inherited from sperm to be destroyed shortly after fertilisation...
An extensive study examining human embryos created using mitochondrial donation has demonstrated that the technique does not adversely affect embryo development...
A study has found that stem cells from older people accumulate high numbers of mitochondrial DNA mutations, which could limit their therapeutic value...
A test which measures mitochondrial DNA levels in the embryo could help increase IVF success rates, scientists claim...
Given the complexity of the technology, costs and risks involved, two recently described mitochondrial 'gene-correction' strategies will probably remain as proof-of-concept studies and are unlikely be of practical use in clinical medicine in the foreseeable future...
Scientists in the USA have demonstrated how stem cell techniques may benefit people with incurable mitochondrial diseases. The research suggests it might be possible one day to replace diseased tissue in patients affected by the disorders...
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.