Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
Mutation
A change in the sequence of DNA. Mutations occurring in genes may prevent them from working properly, which might result in disease (a genetic condition). Mutations occur naturally at a low rate, but can also be induced by radiation and some chemicals.
1426 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Comprehensive mutation map shows effects of key cancer gene
Not all mutations in the CTNNB1 gene — a key cancer driver — are equal, offering insights for personalised cancer treatment...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Radio Review: The Life Scientific – Professor George Church
Professor Jim Al-Khalili interviews Professor George Church in this episode of The Life Scientific. From bringing back mammoths to the Human Genome Project... but does he ask probing enough questions? Davy Tennison finds out for BioNews...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
AI interprets complex human genome sequences
A novel artificial intelligence tool has been developed to predict the molecular and regulatory effects of genetic variants relevant to health and disease...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Book Review: The Social Genome – The new science of nature and nurture
Are we on a path predetermined by the genes we inherit, or are we a product of the social environment with which we interact? Dr Helen Robertson reviews the new book written by sociologist Professor Dalton Conley...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
CRISPR/Cas3 genome editing shows promise in treating protein misfolding disease
A new genome editing approach has been shown to safely and efficiently remove the source of transthyretin amyloidosis in mice, demonstrating greater therapeutic opportunities for genome editing...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
TV Review: Hitler's DNA – Blueprint of a dictator
Hitler's DNA has been identified and sequenced for the first time. Senior science writer, Dr Matteo Cortese, reviews a BBC programme investigating what the DNA reveals about Hitler's heritage – discussing the technology at its core: polygenic scores...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Genes linked to brain development revealed by CRISPR genome editing
A large-scale study has unveiled genes essential for early brain development and uncovered the cause of a previously unrecognised neurodevelopmental disorder...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Geneticists recognised in New Year Honours
Pioneering geneticists Professor Zosia Miedzybrodzka and Professor Meena Upadhyaya were both recognised in the King's 2026 New Year Honours list...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Expanded Carrier Screening: How Is It Used? What Are the Ethical Implications?
The first session of 'What Does Genomics Mean for Fertility Treatment?' – the 2025 Annual Conference of PET – explored the growing use of expanded carrier screening...