Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
PGT (preimplantation genetic testing)
A group of techniques that look at the genetic material of embryos created through IVF. These include:
- PGT-M: preimplantation genetic testing for monogenic conditions (previously considered a form of PGD, or preimplantation genetic diagnosis)
- PGT-SR: preimplantation genetic testing for structural chromosome rearrangements (previously considered a form of PGD, or preimplantation genetic diagnosis)
- PGT-A: preimplantation genetic testing for aneuploidy (previously known as PGS, or preimplantation genetic screening)
- PGT-P: preimplantation genetic testing involving polygenic scores
91 articles
Class action lawsuits against genetic testing companies over PGT-A
Former IVF patients in the USA have filed class action lawsuits against several companies for misleading them about the efficacy of PGT-A...
Image by Alan Handyside via the Wellcome Collection. Depicts a human egg soon after fertilisation, with the two parental pronuclei clearly visible.
Book Review: Baby X
In this dystopian novel, eggs or sperm can be created from any person's cells, resulting in celebrities facing the alarming potential of meeting biological children they never conceived...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Fertility trends: Outcomes improve but NHS cycles down
The most recent HFEA data provides a window on trends in the UK fertility sector, writes Ephia Yasmin...
Polygenic embryo screening – Patient perspectives and concerns
It is crucial to focus not just on scientific concerns about PGT-P, but also on broader potential consequences for those who could be impacted by the technology, explains Maria Siermann...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Event Review: Polygenic Embryo Screening – The promise and perils of selecting our children's traits
A timely conversation focused on the bioethical concerns wrapped up in the clinical use of polygenic embryo screening...
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
Event Review: The Impact of Dobbs on Emerging Reproductive Technologies
Doctors and lawyers got together to discuss the intricacies of the impact of the overturning of Roe v Wade on reproductive healthcare in the USA…
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Fertility add-ons in Canada: Is it time to end the silence?
Emeritus Professor, Arthur Leader, discusses the use of IVF treatment add-ons in Canada...
Image by Alan Handyside via the Wellcome Collection. Depicts equipment used for embryo biopsy.
Equity of access: Not for northern NHS patients requiring PGT-M
The most northerly fertility clinic offering NHS funded PGT-M and PGT-SR in England is in Nottingham. This means there are now around 100 patients residing in the north of England who are unable to access the NHS fertility services they need locally to avoid transmitting a genetic condition to their children…
The ethics of preimplantation genetic testing using polygenic scores
Academics from Oxford University discuss the ethics surrounding preimplantation genetic screening tests, including the use of polygenic risk scores...