CRISPR Associated Proteins are enzymes that associate with CRISPR RNAs to bind to and alter DNA or RNA target sequences.
Cas enzymes originate in bacteria and as such a wide variety of types exist. Some are used for genome editing or editing RNA.
There are also versions that have been altered in the lab to perform specific tasks. Common examples include Cas9 which makes a double-stranded break in a target DNA sequence, and Cas13 which targets RNA.
Genome editing using small protein structures has the potential to be more efficient, with increased specificity, than current methods – such as CRISPR/Cas genome editing...
This piece by Vanessa Burns, exploring the impact that CRISPR-based genome editing will have over the next 25 years, won the second prize in the inaugural Marcus Pembrey BioNews Writing Competition...
A genome editing technique that allows researchers to test thousands of different mutations that might affect how cancer cells behave has been developed...
Two potential new treatments for Alzheimer's disease using the CRISPR genome editing approach have been reported at the Alzheimer's Association International Conference, in Amsterdam, the Netherlands...
A new genome editing mechanism has been developed for the first time from a protein found in eukaryotes...
Cells in early human embryos are unable to effectively repair the double-stranded DNA breaks made during CRISPR/Cas9-based genome editing...
A novel CRISPR-based gene therapy has been shown to reduce the level of antibiotic resistant E. coli within the gastrointestinal tract...
Subscribe for free to what PET does best – informing you of the latest in fertility, genomics and embryo research.
