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BioNews

Germline

Relating to genetic information that can be inherited by the next generation (the DNA in egg and sperm cells, and their precursors).

76 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Comment
7 March 2022 • 6 minutes read

Editing the Human Genome: Where Are We Now? What Happens Next?

by Dr Alexander Ware

The Progress Educational Trust recently arranged a lineup of key figures at the vanguard of different aspects of genome editing, who, during the event, canvassed their opinions and current research...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Reviews
16 April 2021 • 6 minutes read

Book Review: CRISPR People — The science and ethics of editing humans

by Jonathan Bestwick

In November 2018, the Chinese scientist Dr He Jiankui announced to attendees of the second International Summit on Human Genome Editing that he had used the CRISPR genome editing approach to modify the DNA of embryos before implanting them in their mother's uterus...

Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the sequencing output from an automated DNA sequencing machine.
Reviews
12 March 2021 • 4 minutes read

Event Review: Curing the Incurable — The promises of genome editing

by Dr Yvonne Collins

Scientific American in partnership with Cellectis, hosted a virtual event to explore genome editing and its use in the clinic. Three pioneers of the field were invited to discuss the early days of genome editing, new technologies and future challenges...

Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family entwined in coils of DNA (based on the figure of Laocoön from Greek and Roman mythology).
Comment
11 February 2021 • 4 minutes read

The 14-day limit should be extended to 28 days

by Sophia McCully

The '14-day rule', initially proposed in 1979 in the USA, was first recommended in the UK by the Warnock Committee in 1984. It limits research on intact human embryos 'prior to 14 days' gestation or the beginning of primitive streak formation' and is part of the Human Fertilisation and Embryology Act 2008...