Egg maturation supported by stem cells results in first live birth
The first live human birth using a novel technology that uses induced pluripotent stem cells to support egg maturation outside the body has been reported...
BioNews
In vivo
Latin for 'within the living', referring to processes taking place within a living organism.
51 articles
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
First patient receives novel in vivo gene therapy for blood cancer
A novel gene therapy approach that directly targets immune cells within a patient's body has been trialled in a B-cell cancer patient...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
CRISPR therapy tested on more patients with genetic inflammatory disorder
Positive Phase 2 results for an investigational CRISPR genome editing treatment for hereditary angioedema have been announced...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Mouse testicle organoids grown in lab
Organoids grown from testicular cells of young mice have shown characteristics of normal mouse testes and have potential to produce sperm...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Key genes associated with DNA damage identified
145 genes have been identified as key to maintaining genome stability, protection, repair, and preventing DNA damage...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
CRISPR base editing therapy cuts high cholesterol in early trial
CRISPR base editing therapy reduced cholesterol levels in the blood of a small cohort of patients, clinical trial interim data has shown...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Chimeric primate created using embryonic stem cells is born
A chimeric monkey has been created using embryonic stem cells with two different sets of genes, a new study has demonstrated...
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Are human embryo models embryos?
Dr Calum MacKellar discusses the biological, moral and legal status of stem-cell-based embryonic entities...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Blood test predicts increased risk of developing pre-eclampsia
A blood test taken in the first trimester of pregnancy to measure cell-free DNA methylation can help to predict the risk of preterm pre-eclampsia...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene variant in people of African ancestry influences HIV replication
A genetic variant found in people of African ancestry may help explain naturally occurring lower viral loads of HIV-1...