Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
Mutation
A change in the sequence of DNA. Mutations occurring in genes may prevent them from working properly, which might result in disease (a genetic condition). Mutations occur naturally at a low rate, but can also be induced by radiation and some chemicals.
1430 articles
Image by Sílvia Ferreira, Cristina Lopo and Eileen Gentleman via the Wellcome Collection. Depicts a single human stem cell embedded within a porous hydrogel matrix (false colour).
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Child dies after experimental genome editing in China
A six-year-old girl has died following an experimental genome editing treatment, prompting an investigation into the clinical trial by the university involved...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Personalised gene therapy shows promise for rare childhood epilepsy
A new personalised genetic therapy has shown early success in treating two children with a rare genetic epilepsy syndrome...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Inherited genetics could influence how cancers develop after DNA damage
Inherited genetic differences may help explain why people exposed to the same cancer risk factors, such as smoking and ultraviolet radiation, do not all develop cancer, according to research in mice...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
First UK child receives gene therapy for inherited sight loss
An 11-year-old girl has become the first UK patient to receive an experimental gene therapy for an inherited eye disorder...
Donor Conception and Genetic Disease: Lessons to Be Learned from Donor 7069
Seven experts discussed the sensitive case of donor 7069 and explored what could be done to avoid it happening again, as well as how to improve outcomes if it did...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
FDA opens path to approval for Hunter syndrome gene therapy
The US Food and Drug Administration is allowing biotech company Regenxbio to reapply for licensing of a gene therapy for Hunter syndrome, in a reversal of its previous decision...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Ebola virus continues active replication in brain tissue models
Three-dimensional cerebral organoids suggest that Ebola virus can establish long-term infection in the human brain...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.