BioNews
Mutation
A change in the sequence of DNA. Mutations occurring in genes may prevent them from working properly, which might result in disease (a genetic condition). Mutations occur naturally at a low rate, but can also be induced by radiation and some chemicals.
Two gene therapies for sickle cell disease approved by FDA
Two gene therapies for the treatment of sickle cell disease have been approved by the US Food and Drug Administration...
Hormone surge reveals link between genetics and pregnancy sickness
A hormone produced by the fetus and placenta is directly related to nausea and vomiting experienced by many women during pregnancy...
Direct link established between fertility related genes and lifespan
Genetic mutations linked with promoting early reproductive health have been associated with shorter lifespan, aligning with an evolutionary theory of ageing dating back to 1957...
Gene variant that helps regulate body weight discovered
A gene variant that affects appetite control could lead to new strategies for treating obesity...
Genome profiling at birth – is this the future we want for our children?
Professors Helen Firth, Clare Turnbull and Anneke Lucassen and Dr Robin Lachmann respond to the publication of an initial list of 223 rare conditions that will be investigated as part of Genomics England's Generation Study...
Research into gene therapy reveals blood cancer risk
A gene therapy treatment for sickle cell disease has led to a build-up of cells with genetic mutations that make them grow faster, increasing blood-cancer risk, researchers revealed...
Unintended consequence of CRISPR/Cas9 genome editing discovered
CRISPR/Cas9 genome editing can result in the unintended deletion of a region associated with cancer...
First CRISPR therapy evaluated by FDA advisers
A CRISPR-based treatment for sickle cell disease is one step closer to approval after an advisory committee for the US Food and Drug Administration met to review its safety...