A genome-editing platform that uses an enzyme (Cas9) to make a double-stranded break at a specific location in the genome, directed by a guide RNA.
CRISPR/Cas9 has been used to identify genome editing targets that significantly enhance the efficiency of a targeted therapy for myeloma, a type of cancer...
A CRISPR-based tongue swab test has been developed to diagnose of tuberculosis infections...
Side effects of viral-delivered gene therapies have been elucidated using human stem-cell derived kidney organoids...
A new AI model can predict DNA repair following CRISPR-based genome editing, suggesting how to achieve more accurate gene insertions...
A gene involved in how the body absorbs and uses vitamin D has been found to influence essential pathways related to cellular metabolism and cancer growth...
A precision genome editing approach has successfully corrected harmful mutations in mitochondrial DNA, offering new hope for treating currently incurable mitochondrial diseases...
A long-running legal battle over patent rights for the Nobel-prize-winning CRISPR/Cas9 approach to genome editing has reignited...
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