Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
BioNews
CRISPR/Cas9
A genome-editing platform that uses an enzyme (Cas9) to make a double-stranded break at a specific location in the genome, directed by a guide RNA.
289 articles
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
Gene critical in vitamin D metabolism linked to cancer
A gene involved in how the body absorbs and uses vitamin D has been found to influence essential pathways related to cellular metabolism and cancer growth...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Base editing corrects mitochondrial DNA mutation in human cells
A precision genome editing approach has successfully corrected harmful mutations in mitochondrial DNA, offering new hope for treating currently incurable mitochondrial diseases...
Image by Bill Sanderson via the Wellcome Collection, © Wellcome Trust Ltd 1990. Depicts Laocoön and his family (from Greek and Roman mythology) entwined in coils of DNA.
CRISPR Nobel laureates win latest round of patent dispute
A long-running legal battle over patent rights for the Nobel-prize-winning CRISPR/Cas9 approach to genome editing has reignited...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
CRISPR base editing treats baby born with rare metabolic disease
A baby born with a rare genetic liver disease has received the world's first customised experimental treatment that involved directly repairing his DNA to fix a faulty protein...
Image by Matthew Daniels via the Wellcome Collection. Depicts human cells, showing the stages of cell division.
Image by Christoph Bock/Max Planck Institute for Informatics via Wikimedia Commons. Depicts a DNA molecule that is methylated on both strands on the centre cytosine.
David Liu, pioneer of base editing and prime editing wins major science prize
Professor David Liu, the developer of base editing and prime editing, has won the Breakthrough Prize in Life Sciences, the largest annual monetary award in science...
Image by Peter Artymiuk via the Wellcome Collection. Depicts the shadow of a DNA double helix, on a background that shows the fluorescent banding of the output from a DNA sequencing machine.
'Woolly' mouse with mammoth traits created
Mice have been created with woolly mammoth-inspired traits using genome editing in de-extinction efforts.