A genome-editing platform that uses an enzyme (Cas9) to make a double-stranded break at a specific location in the genome, directed by a guide RNA.
A baby born with a rare genetic liver disease has received the world's first customised experimental treatment that involved directly repairing his DNA to fix a faulty protein...
Professor David Liu, the developer of base editing and prime editing, has won the Breakthrough Prize in Life Sciences, the largest annual monetary award in science...
Mice have been created with woolly mammoth-inspired traits using genome editing in de-extinction efforts.
Gene therapy, Casgevy, has been recommended for use on the NHS in England for some people living with a severe form of sickle cell disease...
A novel gene insertion therapy may be able to cure infants of a rare genetic liver disease...
A novel way to control CRISPR genome editing using focused ultrasound has been discovered...
How ageing induces iron insufficiency, reduces stem cell renewal and tumour formation has been discovered...
A molecule that can be used to enhance CRISPR genome editing also causes unintended destruction of large sections of the genome in human cells...
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