A genome-editing platform that uses an enzyme (Cas9) to make a double-stranded break at a specific location in the genome, directed by a guide RNA.
Data on the effectiveness and safety of Casgevy gene therapy in children aged five to 11 years has been reported...
CRISPR-based genome editing has been used to overcome chemotherapy resistance in lung tumours by disabling a tumour-specific mutation...
Two gene therapy trials run by Intellia Therapeutics have been paused after a study participant was hospitalised...
CAR-T cell cancer treatments could be made safer and more durable by reprogramming T cells without altering their DNA, according to new research...
CRISPR/Cas9 has been used to identify genome editing targets that significantly enhance the efficiency of a targeted therapy for myeloma, a type of cancer...
A CRISPR-based tongue swab test has been developed to diagnose of tuberculosis infections...
Side effects of viral-delivered gene therapies have been elucidated using human stem-cell derived kidney organoids...
A new AI model can predict DNA repair following CRISPR-based genome editing, suggesting how to achieve more accurate gene insertions...
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