Sperm self-destruction may lie behind maternal mitochondrial inheritance
Researchers have identified a gene that, when activated, causes mitochondria inherited from sperm to be destroyed shortly after fertilisation...
Unusual patterns of inheritance related to mutations in genes found in the mitochondria. Mitochondrial DNA is always maternally inherited, since sperm contribute no mitochondria when they fertilise the egg.
Researchers have identified a gene that, when activated, causes mitochondria inherited from sperm to be destroyed shortly after fertilisation...
A study has identified a potential problem with mitochondrial donation, an IVF technique that aims to prevent the transmission of faulty mitochondria from mother to child...
The US NAS has published a report on the ethical, social and policy considerations relating to mitochondrial replacement techniques. The recommendation that has inevitably attracted most attention, however, is that only male embryos should be transferred, an approach that was considered but rejected in the UK...
We report from the second session of the annual conference of the Progress Educational Trust, titled 'From Three-Person IVF to Genome Editing: the Science and the Ethics of Engineering the Embryo', about the newly legalised process of mitochondrial donation...
Regulations that came into force this week will enable the UK to be the first country in the world to allow the use of mitochondrial donation techniques during IVF...
Given the complexity of the technology, costs and risks involved, two recently described mitochondrial 'gene-correction' strategies will probably remain as proof-of-concept studies and are unlikely be of practical use in clinical medicine in the foreseeable future...
Scientists in the USA have demonstrated how stem cell techniques may benefit people with incurable mitochondrial diseases. The research suggests it might be possible one day to replace diseased tissue in patients affected by the disorders...
by Sandy Starr
The House of Commons voted by 382 to 128 to pass regulations permitting mitochondrial donation, a majority of 254...
by Sandy Starr
A group of backbench MPs, led by Conservative MP Fiona Bruce, has sought to delay the laying before Parliament of regulations permitting the use of mitochondrial replacement techniques...
The UK Government has announced that regulations around the use of mitochondrial replacement techniques will be presented to Parliament in the next few months...
BioNews, published by the Progress Educational Trust (PET), provides news and comment on genetics, assisted conception, embryo/stem cell research and related areas.