3D genome structure forms before gene activation in early embryos
A three-dimensional structure of DNA begins forming before an embryo's own genes switch on...
The single cell formed immediately after fertilisation, once the genetic information of the egg and sperm have fused.
A three-dimensional structure of DNA begins forming before an embryo's own genes switch on...
A novel method for visualising human blastocyst development – which has led to findings with implications for PGT-A – is described by Dr Ahmed Abdelbaki, a postdoctoral researcher in the Niakan Lab at the University of Cambridge...
An embryo that originally had three pronuclei resulted in a healthy baby after one pronucleus was microsurgically removed...
Several epigenetic pathways have been found to play a role in the spatial organisation of DNA during early embryonic development in mice...
Mice have been created with woolly mammoth-inspired traits using genome editing in de-extinction efforts.
Mice with two fathers have been created using genome editing, and have survived into adulthood...
During the first cell divisions of mouse embryos a period of instability has been uncovered, which translates into chromosomal errors...
by Dr Geraldine Jowett and 1 others
Identifying the defining characteristics of different states of stem cell pluripotency could hold the key to improving human stem cell-based embryo models...
The discovery of a protein responsible for binding and fusing sperm and egg cells in mice could shed light on possible causes of fertility and treatments for it...
Changes that occur to DNA that could cause IVF embryos to stop dividing have been identified...
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